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May 18, 2018 · A genetic disorder is a disease caused in whole or in part by a change in the DNA sequence away from the normal sequence. Genetic disorders can be caused by a mutation in one gene (monogenic disorder), by mutations in multiple genes (multifactorial inheritance disorder), by a combination of gene mutations and environmental factors, or by damage to chromosomes (changes in the number or ... Dec 11, 2017 · The faulty gene of ADPKD causes a problem in the wall (membrane) of cells in certain parts of the body, in particular certain kidney cells. The fault in the cells leads to the development of cysts. In fact, with ADPKD, two faulty genes have been identified that can cause the condition. Aug 03, 2020 · It was the ninth-leading cause of death in the nation due to the rise of rise in obesity and Type 2 diabetes, according to the Centers for Disease Control and Prevention. ... be chronic kidney ...